Scrutinizing the evidence for breast
cancer procedures and treatments
Bromide Dominance Theory
How Competitive Inhibition Causes Iodine Deficiency
by Lynne Farrow © 2007- 2015 by Lynne Farrow. All rights reserved.

    A bromide dominance condition may develop when bromine,
    acquired through environmental, occupational, iatrogenic or dietary
    exposure, causes bromide levels in the body to rise high enough to
    inhibit iodine enzyme metabolism.

    Iodine supplementation alters the competitive bromine-iodine
    relationship causing bromide excretion. Thus, bromide dominance is
    diminished and  proper iodine enzyme metabolism may be restored.

    In the toxic 21st Century, these questions must be raised:

  • Would we have such a severe iodine deficiency without bromide

  • If iodine deficiency is the underlying cause of many diseases,
    is bromide "the underlying cause of the underlying cause?"

  • Is bromide dominance creating a public health crisis?

    Where Does Bromide Dominance Come From?

    Bromide is an insidious, additive used in many common products, and as a
    pesticide.  Because of the sheer amount of bromide-supplemented
    products,  exposure to this man-made additive has caused a depletion of
    iodine in human populations.  Studies in lab animals provide alarming
    evidence that even small amounts of bromide exposure can be toxic. (1)

    What products contain bromide?

    Currently, bromide is found in pesticides (methyl bromide),  some bread
    products (potassium bromate), brominated vegetable oil that may be
    added to citrus-flavored drinks, hot tub cleansers, certain asthma inhalers
    and prescription drugs, plastic products, some personal care products,
    and some  fabric dyes.

    Effects of Bromide on the Organs

    Iodine depletion weakens the thyroid and other organs. (2)(3)(4)(5)(6)  In
    individuals where the bromide-iodine ratio is less, bromide may not be


    Elevated bromide levels have been implicated in every thyroid disease,
    from simple hypothyroidism to auto-immune diseases to thyroid cancer.
    Malenchenko found bromide levels 50 times higher in thyroid cancer than
    normal thyroid tissue. (7)

    Rats fed even the minimal amount of bromine expected to be encountered
    in the environment underwent goiter-like changes (8),  an arguable case of
    bromide dominance.  In the FIRE project, exposing rats to the brominated
    flame retardant compound, bromocyclodecane, showed consistent effects
    on the thyroid hormone axis, including decreased T4.  Thyroid gland cells
    have increased size and larger nuclei, indicating increased synthetic
    activity. (9)

    With enhanced intake of bromide, fully one-third of the iodine content in
    the thyroids of rats was replaced by bromide. (10)


    Skin biopsied from a woman who had been on bromide-containing
    sedatives for nearly four years  found increased bromide in normal skin
    and three times that in an affected skin lesion. (11)

    An infant administered a syrup containing sodium bromide developed
    vegetative lesions on the face and scalp. (12)

    Technicians exposed to brominated compounds for prolonged periods
    developed multiple cherry angiomas on the trunk and extremities. (12)


    The psychiatry literature abounds with cases of elevated bromide levels
    being implicated in mental conditions from depression to schizophrenia.
    (14)(15)(16) As Guy Abraham, MD, asks, "How many people with
    misdiagnosed bromism are currently treated with psychiatric drugs?"(17)  
    Bromide was used to suppress women's sex drive in the 1950s.


    Potassium bromate, a bread additive, is known to cause renal damage and
    permanent deafness in animals and man. (18)  In the FIRE project, the most
    relevant effect on exposing rats to 28 days to the brominated flame
    retardant compound, tetrabromobisphenol-A, was hearing.  Specifically,
    the lower frequency range was affected . (19)


    The ability of bromate to cause cancer, especially kidney cancer, is a
    significant health concern.  (20)  The gene expression in kidneys in rats
    given a high dose 100-week potassium bromate in their drinking water
    showed marked gene expression difference from the lower non-cancer
    dose.  The high dose kidney gene expression resembled an adenoma-like
    expression pattern. (21)


    Potassium bromate as an additive to most commercial bread and baked
    goods probably provides the most egregious contribution to bromide
    overload in Western cultures.

    Bromated flour is product "enriched"  with potassium bromate.  Some
    commercial bakers claim they use bromated flour because it yields
    dependable results, and it makes more elastic dough which can stand up
    to bread hooks and other commercial baking tools.  (22) However,
    Pepperidge Farm manages to use only unbromated flour with excellent


    The UK banned bromate in bread in 1990.
    Canada banned bromate in bread in 1994. (23)
    Proposal P230 in Australia: Food Regulation Ministerial Council (FSANZ)
    still has not finalized its July 2007 proposal to mandate iodized salt in
    breads, breakfast cereals and biscuits.

    Back in 1999, the Center for Science in the Public Interest petitioned the
    FDA to prohibit the use of potassium bromate, charging that the FDA has
    known for years that bromate causes cancer in lab animals, but has failed
    to ban it. (24)  As of September 2007, the US FDA responded to Breast
    Cancer Choices inquiry with the statement, " Potassium Bromate is still
    listed as a safe additive."

    When drinking water containing bromide is exposed to ozone, bromate
    ion, a powerful oxidizing agent, is formed.  Two significant recalls of
    drinking water involving bromate have occurred:  Wegmann's Food You
    Feel Good About Spring Water Recall in 2006, and Coca-Cola's Dasani in
    2004. (25)

    Potassium bromate is an antiseptic and astringent in toothpaste, mouth
    and gargles.  Very toxic if taken internally.  May cause bleeding and
    inflammation of gums in toothpaste.  (26)

    Flame retardants reduce the flammability of a wide variety of commercial
    and household products.  Some brominated home retardants migrate from
    the products in which they are used and are entering the environment
    and people.  (27)

    Sodium bromate in Products: Permanent Waves, Hair Dyes, Textile Dyes
    Sodium bromate is in permanent wave neutralizers, hair dye material, and  
    the textile dyeing process. (28) Benzalkonium is used as a preservative
    in some cosmetics. (29)


    Breast Cancer Choices is indebted to the pioneering bromide research
    of Guy E. Abraham, MD, as well as the clinical and intellectual
    contributions of David Brownstein, MD, and Jorge Flechas, MD.

    (1)  Vobecky M et al., Interaction of Bromine with Iodine in the Rat Thyroid Gland at Enhanced
    Bromide Intake, Biol Trace Elem Res 1996.
    (2)  Velicky J et al., The Effect of Bromide on the Ultrastructure of Rat Thyrocytes, Ann Anat 2004.
    (3)   Pavelka S et al., Bromide Kinetics and Distribution in the Rat. II Distribution of Bromide in the
    Body, Biol Trace Res 2000.
    (4)   Velicky J et al., Long Term Action of Potassium Bromide on the Rat Thyroid Gland, Acta
    Histochem 1998.
    (5)  Velicky J et al., Potassium Bromide and the Thyroid Gland of the Rat: Morphology and
    Immunochemistry 1997.
    (6) Vobecky M et al., Interaction of Bromine with Iodine in the Rat Thyroid Gland at Enhanced
    Bromide Intake, Biol Trace Elem  Res 1996.
    (7)  Malenchenko AF et al., The Content and Distribution of Iodine, Chlorine and Bromide in the
    Normal and Pathologically Changed Thyroid Tissue, Med Radiol 1984.
    (8).  Velicky J et al., Potassium Bromide and the Thyroid Gland of the Rat: Morphology and
    Immunochemistry, RIA and INAA Analysis, Ann Anat 1997.
    (9)  www.credocluster.info Issue 6, July 2006
    (10) Vobecky M et al., Interaction of Bromine with Iodine in the Rat Thyroid Gland at Enhanced
    Bromide Intake, Biol Trace Elem Res 1996.
    (11)  Hubner K et al., Skin Bromide Content and Bromide Excretion in Bromoderma Tuberosum, Arch Derm
    Res 1976.
    (12)  Bel S et al., Vegetant Bromoderma in an Infant, Pediatric Dermatology 2001.
    (13)  Cohen A et al., Cherry Angiomas Associated with Exposure to Bromides, Dermatology 2001.
    (14) Horowitz BZ et al., Bromism from Excessive Cola Consumption, Clinical Toxicology 1997.
    (15)  Levin M., Transitory Schizophrenia Produced by Bromide Intoxication, Am J Psychiatry 1946.
    (16)  www.gulflink.osd.mil/library/randrep/pb_paper/mr1018.2chap10.html.
    (17) Abraham G., The Combined Measurement of the Four Stable Halides by the Ion-Selective Electrode
    Procedure Following Their Chromatographic Separation on a Strong Anion Exchange Resin: Clinical
    Application, The Original Internist 2006.
    (18)  Morizono T et al., The Effects of Cetrimide and Potassium Bromate on the Potassium Ion
    Concentration in the Inner Ear Fluid of the Guinea Pig, Physiol Bohemoslov 1988.
    (19) www.credocluster.info, Issue 6 2006.
    (20)  www.rtctoc.com/bromate.htm.
    (21)  Geter D et al., Kidney Toxicogenomics of Chronic Potassium Bromate Exposure in F334 Male
    Rats, EIMS Meta Data Report 2006.
    (22) www.wisegeek.com.
    (23)  www.rtctox.com/bromate.htm.
    (24). www.cspinet.org/new/bromide.htm.
    (25)  www.rtctox.com/bromate.htm.
    (26) www.healthy-communications.com/hazards_of_cosmetics_by_carol_barzac95.html.
    (27) www.credocluster.info, Issue 6 2006.
    (28)  www.alibaba.com/catalog/11292709/sodium_bromate_99_5.html.
    (29)  www.gina.antczak.btinternet.co.uk/CU/CUHOME.htm.

"Bromism" symptoms according to the
US Army Investigation:

Report on Bromism

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children's pajamas unless PBDE
flame retardants are found in
hours children spend sleeping
exposes them to toxins from both
mattresses and pajamas.

One study found children carry up
to three times the fire retardant to
three times the fire retardant
chemicals in their blood than their
mothers' did. These chemicals are
linked with a variety of serious

Savvy parents seek out organic
cotton pajamas and untreated
Bromide Fire Retardant Alert for
Children's Pajamas

Look for bread made without bromated flour

Certain Asthma Inhalers Contain Bromide

Certain Antidepressants Contain Bromide
    Paracelsus (1493 - 1541),
    referred to as "the father" of toxicology, is credited
    with the concept, "The dose makes the poison."
Flame Retardants Linked To Lower Birth Weight

News:   August 31, 2011

    Exposure during pregnancy to flame retardant
    chemicals commonly found in the home is linked to
    lower birth weight babies, according to a new study
    led by researchers at the University of California,
    Berkeley’s School of Public Health.

    In the study, published Tuesday, Aug. 30, in the
    peer-reviewed publication American Journal of
    Epidemiology, researchers found that every tenfold
    increase in levels of PBDEs, or polybrominated
    diphenyl ethers, in a mother’s blood during
    pregnancy corresponded to a 115 gram (4.1 ounce)
    drop in her baby’s birthweight.

    “This is the first, large population-based study to
    link PBDEs with babies’ birth outcomes,” said study
    lead author Kim Harley, adjunct assistant professor
    of maternal and child health and associate director
    of the Center for Environmental Research and
    Children’s Health (CERCH) at UC Berkeley. “A 115-
    gram decrease in weight is a fairly significant
    finding. By way of comparison, consider that
    smoking during pregnancy is associated with about
    a 150- to 250-gram decrease in birthweight.”
Breast Cancer ChoicesTM
    The information discussed is not intended to diagnose, treat, cure, or prevent any disease.

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    Contact website editor, Lynne Farrow, with comments or for reprint permission at:
    lynne@breastcancerchoices.org or write us at Breast Cancer Choices, Inc., PO Box 1567,
    Amagansett, NY 11930.

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Flame Retardants Linked To Lower Birth Weight

receptors in the body, causing the potential for iodine deficiency.

PBDE (bromide) fire retardants have been added to mattresses,
carpeting, electronics, furniture, car interiors, electronics, and
other products since 1970. These products disperse toxic bromide

BPDEs are banned in many countries outside the US.  
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