Scrutinizing the evidence for breast
cancer procedures and treatments
    About the Iodine Supplementation Protocol
                --- Not Just For Breast Cancer Patients

    Physicians Guy Abraham, MD, David Brownstein, MD, and Jorge Flechas, MD, have treated
    more than 7,000 patients with iodine supplementation.  The protocol below is suggested by
    their writings and lectures. We acknowledge with appreciation their pioneering research
    and generous contributions to the field of Iodine Therapy.  See references below the

                             Iodine and Companion Nutrients

    From October 2007 Iodine Conference

  • 50 mg Iodoral minimum for breast cancer (may start with 12.5 mg).
    Some practitioners may recommend another form of iodine such as
    Lugol's solution.  Iodoral is the Lugol's formula in tablet form especially
    designed to avoid gastric irritation.

  • Vitamin C - 3,000 mg per day (more may be necessary to detox bromide).

  • 300-600 mg magnesium oxide (Iodine Investigation Project participants
    prefer magnesium glycinate or magnesium citrate.)

  • 200 mcg selenium. The selenomethionine version is preferred by many. Also see

  • 500 mg niacin (B3) twice a day (NOT niacinamide). Start lower to avoid flush. *See
    update in left margin on the ATP Cofactors as an alternative.

  • 100 mg Vitamin B2 three times a day. *See update in left margin on the ATP
    Cofactor as an alternative.

  • A comprehensive vitamin and nutrition program.

  • (Feb 2008) Dr. Guy Abraham cautions that "excess calcium supplementation (2,000-
    3,000 md/day) has been the most common cause of poor response to iodine
    supplementation." Vitamin Research News Vol. 22. Number 2.

                      24 Hour Iodine Loading Test Now Essential

    The Iodine specialists have recently discovered it is essential to have the 24 Hour Iodine
    Loading Test before implementing iodine supplementation in order to investigate the
    presence of a possible iodine absorption defect. If a patient has a normal or high Loading
    Test score in the presence of known iodine deficiency condition such as breast or thyroid
    disease, a defect in the Sodium Iodide Symporter (NIS) mechanism is suspected. The
    iodine taken during the loading test may pass into the urine unabsorbed giving a false
    normal reading. Follow your physician's iodine dosing carefully to see how the iodine test
    result  changes.

  • The doctors find that the most common side effects are usually resolved with 3
    grams of vitamin C and/or the salt loading protocol.

  • Be aware of iodine-related bromide detox symptoms. Symptoms of "bromism" may
    occur in some people. Click here for a list of recorded bromide symptoms. Patients
    are usually advised to cut back on iodine, *pulse-dose (see below) and salt-load
    more frequently.

    Important: The following protocol should be implemented only under your doctor's
    supervision and monitored with the appropriate laboratory work and thyroid studies.
    Report any side effects to your physician. Do not take iodine if you are allergic to iodized

    Salt Loading Protocol for Possible Bromide Side

    Orthoiodosupplementation induced and increased mobilization of bromine from storage
    sites, with increased urinary excretion of bromide. --Guy Abraham, MD

    Certain iodine-literate doctors feel the bromide excreted by iodine therapy can be
    eliminated more efficiently by the chloride present in mineral-rich unprocessed sea salt.
    The salt is added to water in a specific way. Eating salty food is not effective. Table salt is
    only used in an emergency.

    Many iodine takers found the Salt Loading Protocol devised by Dr. William Shevin (and
    presented at the February '07 Iodine Conference) to be effective in eliminating the side
    effects such as bromide sedation, acne, brain fog, brassy taste, mouth sores, frontal
    headache or other symptoms which occur in a small percentage of patients.

  • 1/4 teaspoon salt dissolved in 1/2 cup warm water.  Follow immediately with 12-16
    oz pure water.

  • Repeat in 30-45 minutes if needed. May repeat again until copious urination begins.

  • Observe subjective response (usually within several hours).

  • Iodine Investigation Project participants have found 1/2 teaspoon salt dissolved in
    the recommended amount of water works faster than the 1/4 teaspoon dosage.


    1.  Brownstein, Why You Need It, Why You Can't Live Without It, (Third Edition) Medical Alternative Press,
    West Bloomfield, MI 2006. See drbrownstein.com.

    2. Abraham, GE, The Historical Background of the Iodine Project, The Original Internist 2005

    3. Abraham, GE, Iodine Supplementation Markedly Increases Urinary Excretion of Fluoride and Bromide,
    Townsend Letter 2003

    4. Abraham, G.E., Brownstein, D., Evidence that the administration of Vitamin C improves a defective
    cellular transport mechanism for iodine: A case report. The Original Internist, 12(3):125-130, 2005

    [excerpt] Elevated bromide levels were observed in urine and serum samples, twenty times the levels
    reported in the literature in normal subjects(8,9). Mild bromism may have been the cause of the oxidative
    damage to the iodine transport system and the side effects to orthoiodosupplementation. Chloride
    competes with bromide at the renal level and increases the renal clearance of bromide (10,11). Sodium
    chloride at 10 gm/day for one week resulted in marked increase in urine bromide levels, and a sharp
    drop in serum bromide. While on the chloride load, urinary frequency improves for the first time in 5
    years, but fatigue worsened and she experienced facial and body acne. No significant change in
    symptomatology was observed while on Vitamin C. The responses of her symptoms to various
    treatments modalities by self-assessment are summarized in Table I. The treatment modalities are
    cumulative and added sequentially in the patient's management. Measurements of serum and urine
    bromide and iodide levels reported in this manuscript were performed by ion-selective electrode assay,
    following chromatography on strong anion exchanger cartridges, as previously described (3,7).


    The statements above have not been evaluated by the U.S. Food & Drug Administration.  The
    supplements discussed are not intended to diagnose, treat, cure, or prevent any disease.  Do not take
    iodine without the supervision of an Iodine-Literate Doctor who is qualified to interpret lab work in the
    context of supplementation. This website is intended as information only. The editors of this site are not
    medically-trained. Please consult your licensed health care practitioner before implementing any health

    The information provided on this site is designed to support, not replace, the relationship that exists
    between a patient/site visitor and his/her existing physician. This site accepts no advertising. The
    contents of this site are copyrighted 2004-2014 by Breast Cancer Choices, Inc., a 501 (c) (3) Nonprofit

    Contact us with comments or for reprint permission at admin@breastcancerchoices.org


Iodine Investigation
Project participants using
the ATP CoFactors  
Formula report they are
absorbing iodine faster.

Optimox now
manufacturers ATP
Cofactors which seems to
be helping some people
who were not absorbing
iodine efficiently.

• Combination of Vitamins
B2 and B3 in sustained-
release form
• Improves ATP (cell
energy) production
• Enhances transport and
liberation of iodine in
target tissues
• May help improve
muscle soreness
associated with
fibromyalgia, when used
with Iodoral.

  • DETOX bromide
    with salt water

  • HEAL damaged
    iodine absorption
    mechanism with anti-

  • FEED tissues with
    iodine and
    companion nutrients.
Breast Cancer Choices'
3 Part Iodine Strategy
Breast Cancer ChoicesTM

Suggested by the
moderators of the online
iodine groups:

1/2 teaspoon unprocessed
sea salt has been added
to the Iodine Protocol by
Yahoo Iodine Group with
consensus of Breast
Cancer Choices.
We agree that the
properties of salt for
adrenal support and
general detox are
Home    FAQ    Strategies    Discussion    Iodine   Hormones    Contact    Store

Editor's note: Breast
Cancer Choices and
the patient to patient
community find the
start low, start
slow strategy"
to be
most effective in
sensitive cases.
How low? One drop of
Lugol's diluted with 10
drops of water applied
to the skin, per day or
even per week to start.
Iodine supplementation
requires a systematic
approach. Do not try this
without reading the Iodine
books by David
Brownstein, MD, and The
Iodine Crisis Lynne Farrow.

The details of iodine detox
strategies are laid out,
including the "pulse dosing"
technique discovered by
the Breast Cancer Choices
Iodine Investigation Project,
now the Gold Standard
among Iodine
Literate Practitioners.